Fluid Phase Clq Binding Assay

Cereblon Binding Assay Kit

79899 BPS Bioscience 96 rxns. 600 EUR
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

Binding Assay Laboratories manufactures the fluid phase clq binding assay reagents distributed by Genprice. The Fluid Phase Clq Binding Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other Fluid products are available in stock. Specificity: Fluid Category: Phase Group: Clq Binding

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Clq Binding information

Cell Meterâ„¢ Live Cell Caspase 8 Binding Assay Kit *Green Fluorescence*

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Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence*

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Cell Meterâ„¢ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence*

20119-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

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Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

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Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

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abx294056-100g Abbexa 100 µg Ask for price

Total Iron Binding Capacity (TIBC) Assay Kit

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Cell Meterâ„¢ Live Cell Caspase 3/7 Binding Assay Kit *Red Fluorescence*

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