Development and Validation of an RNA Sequencing Assay for Gene Fusion Detection in Formalin-Fixed, Paraffin-Embedded Tumors

RNA sequencing (RNA-seq) is a well-validated tool for detecting gene fusions in fresh frozen tumors, whereas it is much more challenging to use it with formalin-fixed paraffin-embedded (FFPE) tumor samples. We evaluated the performance of RNA-seq to detect gene fusions in clinical FFPE tumor samples. Our assay identified all 15 spiked-in NTRK fusions from RNA reference material and 6 known fusions from 5 cancer cell lines. Limit of detection for the assay was assessed with a series of dilutions of RNA from the cell line H2228. These fusions can be detected when the dilution is down to 10%.

Good intra- and inter-assay reproducibility was observed in three specimens. For clinical validation, the assay detected 10 of 12 fusions initially identified by a DNA panel (covering 23 gene fusions) in clinical specimens (83.3% sensitivity), whereas one fusion (MET fusion) was identified in another 34 fusion-negative tumor specimens as determined by the DNA panel (negative prediction value of 94.3%). This MET fusion was confirmed by RT-PCR and Sanger sequencing, which demonstrated that this is a false negative for DNA panel. The assay also identified 26 extra fusions not covered by the DNA panel, and 20 of them (76.9%) were validated by RT-PCR and Sanger sequencing. Therefore, this RNA assay has reasonable performance and could be a complement to DNA-based next-generation sequencing assays.

Manufacture of rapid pressure-sensitive adhesive microwofit for pressure sensing and fluorescence detection specific to sequence bacterial plasmid gene sequences related to sepsis

Microbial resistance to antibiotics currently available poses a large threat in the global struggle against infections. An important step in determining the resistance to bacterial antibiotics can be a selective DNA sequence capture and fluorescence labeling. In this article, we demonstrate the manufacture of simple, robust and inexpensive microfluidic devices for DNA capture and fluorescence detection of a model antibiotic resistance genes sequence.

We, micromachine laser micromachine polymethacrylate polymethacrylate polymethacrylate polymethacrylate microchannels and closures using pressure-sensitive adhesive tapes. We then formed porous polymeric monoliths with DNA capture probes in these microchannels and used for capture, fluorescent labeling and fluorescence detection induced by the sequence of picomolar concentrations (PM) of genes targets of genes. Resistance to synthetic antibiotics and plasmids. The relative fluorescence for eluting peaks increased with a loaded target DNA concentration. We observed a higher fluorescence signal and percent recovery for synthetic target DNA with respect to plasmid DNA at the same loaded target concentration.

A non-target gene has been used for control experiments and product <3% capture relative to the same target concentration. The comprehensive analysis process includes the manufacture of devices has been completed in less than 90 minutes with a 30-hour detection limit. The simplicity of the manufacture of devices and a good capture capture of the DNA demonstrated here have an application potential with methods of extracting the bacterial plasmid DNA and counting to a single particles to facilitate Determining the susceptibility to antibiotics. Graphic summary.

The combined detection of immune genes to predict the prognosis of patients with non-small cell lung cancer

Lung cancer is one of the main causes of cancer-related death. In recent years, there has been growing interest in the fields of tumor and immunity. This study focused on the possible prognostic value of immune genes in patients with non-cell lung cancer. We used the Atlas of the Cancer Genome (TCGA) to download gene expression data and clinical information from lung adenocarcinoma (LUAD) and pulmonary pulmonary carcinoma (LUC). The list of immune genes has been downloaded from the Import database. We then built prognostic models of immune genes based on the regression analysis of the COX.

We also evaluated the clinical significance of the models via survival analysis, receiver operating characteristic curves (ROC) and an independent prognostic factor analysis. In addition, we analyzed the associations of prognostic models with mutation loads and neo-Engens. Using the OMNiBus (GEO) and Kaplan-Meier Genic Expression Databases, we evaluated the validity of the prognostic models. The PRONOSTIC model of LUAD included 13 immune genes and the prognostic model of LUSC contained 10 immune genes. High-risk patients based on prognostic models had a 5-year survival rate lower than low-risk patients.

Lymphocyte Activation Gene 3 (LAG3) Antibody
20-abx102895	Abbexa	360.00 EUR 159.60 EUR 961.20 EUR 510.00 EUR 309.60 EUR	100 ug 10 ug 1 mg 200 ug 50 ug
Lymphocyte Activation Gene 3 (LAG3) Antibody
20-abx007220	Abbexa	493.20 EUR 710.40 EUR 218.40 EUR 376.80 EUR	100 ul 200 ul 20 ul 50 ul
Lymphocyte Activation Gene 3 (LAG3) Antibody
20-abx109319	Abbexa	493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Lymphocyte Activation Gene 3 (LAG3) Antibody
20-abx130069	Abbexa	526.80 EUR 159.60 EUR 1479.60 EUR 710.40 EUR 393.60 EUR	100 ug 10 ug 1 mg 200 ug 50 ug
Lymphocyte Activation Gene 3 (LAG3) Antibody
20-abx113548	Abbexa	878.40 EUR 477.60 EUR	150 ul 50 ul
Lymphocyte Activation Gene 3 (LAG3) Antibody
abx033099-400ul	Abbexa	400 ul	627.6 EUR
Lymphocyte Activation Gene 3 (LAG3) Antibody
abx033099-80l	Abbexa	80 µl	343.2 EUR
Lymphocyte Activation Gene 3 (LAG3) Antibody
20-abx323649	Abbexa	376.80 EUR 292.80 EUR	100 ug 50 ug
Lymphocyte Activation Gene 3 (LAG3) Antibody
20-abx211362	Abbexa	493.20 EUR 360.00 EUR	100 ul 50 ul
Lymphocyte Activation Gene 3 (LAG3) Antibody
20-abx173393	Abbexa	393.60 EUR 978.00 EUR 510.00 EUR 184.80 EUR 309.60 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Recombinant Lymphocyte Activation Gene 3 (LAG3)
4-RPB663Hu01	Cloud-Clone	560.83 EUR 273.60 EUR 1773.12 EUR 671.04 EUR 1222.08 EUR 451.20 EUR 4252.80 EUR	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Lymphocyte Activation Gene 3 expressed in: E.coli
Recombinant Lymphocyte Activation Gene 3 (LAG3)
4-RPB663Mu01	Cloud-Clone	593.09 EUR 282.00 EUR 1894.08 EUR 711.36 EUR 1302.72 EUR 472.80 EUR 4555.20 EUR	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Lymphocyte Activation Gene 3 expressed in: E.coli
Recombinant Lymphocyte Activation Gene 3 (LAG3)
4-RPB663Ra01	Cloud-Clone	612.44 EUR 286.80 EUR 1966.66 EUR 735.55 EUR 1351.10 EUR 484.80 EUR 4736.64 EUR	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Lymphocyte Activation Gene 3 expressed in: E.coli
Lymphocyte Activation Gene 3 (LAG3) Antibody (Biotin)
20-abx105630	Abbexa	493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Lymphocyte Activation Gene 3 (LAG3) Antibody (HRP)
20-abx108468	Abbexa	493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Lymphocyte Activation Gene 3 (LAG3) Antibody (FITC)
20-abx107047	Abbexa	493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Lymphocyte Activation Gene 3 (LAG3) Antibody (RPE)
abx414103-100tests	Abbexa	100 tests	710.4 EUR
Lymphocyte Activation Gene 3 (LAG3) Antibody (RPE)
abx414104-25tests	Abbexa	25 tests	376.8 EUR
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Human)
4-PAB663Hu01	Cloud-Clone	286.80 EUR 2869.20 EUR 717.60 EUR 358.80 EUR 253.20 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Activation Gene 3 (LAG3)
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Mouse)
4-PAB663Mu01	Cloud-Clone	291.60 EUR 2948.40 EUR 735.60 EUR 366.00 EUR 254.40 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Activation Gene 3 (LAG3)
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Rat)
4-PAB663Ra01	Cloud-Clone	301.20 EUR 3091.20 EUR 768.00 EUR 379.20 EUR 258.00 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Rat Lymphocyte Activation Gene 3 (LAG3)
Rat Lymphocyte Activation Gene 3 (LAG3) Protein
20-abx167681	Abbexa	861.60 EUR 343.20 EUR 2648.40 EUR 1011.60 EUR 610.80 EUR	100 ug 10 ug 1 mg 200 ug 50 ug
Mouse Lymphocyte Activation Gene 3 (LAG3) Protein
20-abx067838	Abbexa	828.00 EUR 343.20 EUR 2548.80 EUR 978.00 EUR 594.00 EUR	100 ug 10 ug 1 mg 200 ug 50 ug
Human Lymphocyte Activation Gene 3 (LAG3) Protein
20-abx067839	Abbexa	777.60 EUR 326.40 EUR 2397.60 EUR 927.60 EUR 560.40 EUR	100 ug 10 ug 1 mg 200 ug 50 ug
Human Lymphocyte activation gene 3 protein (LAG3)
1-CSB-EP012719HU1	Cusabio	456.00 EUR 256.80 EUR 1570.80 EUR 672.00 EUR 1047.60 EUR 314.40 EUR	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Lymphocyte activation gene 3 protein(LAG3),partial expressed in E.coli
Goat Lymphocyte-Activation Gene 3 ELISA kit
E06L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Goat Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Lymphocyte-Activation Gene 3 ELISA kit
E06L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Goat Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Lymphocyte-Activation Gene 3 ELISA kit
E06L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Goat Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Lymphocyte-Activation Gene 3 ELISA kit
E04L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Rabbit Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Lymphocyte-Activation Gene 3 ELISA kit
E04L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Rabbit Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Lymphocyte-Activation Gene 3 ELISA kit
E04L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Rabbit Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Lymphocyte-Activation Gene 3 ELISA kit
E01L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Human Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Lymphocyte-Activation Gene 3 ELISA kit
E01L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Human Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Lymphocyte-Activation Gene 3 ELISA kit
E01L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Human Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Lymphocyte-Activation Gene 3 ELISA kit
E03L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Mouse Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Lymphocyte-Activation Gene 3 ELISA kit
E03L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Mouse Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Lymphocyte-Activation Gene 3 ELISA kit
E03L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Mouse Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Lymphocyte-Activation Gene 3 ELISA kit
E09L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Monkey Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Lymphocyte-Activation Gene 3 ELISA kit
E09L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Monkey Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Lymphocyte-Activation Gene 3 ELISA kit
E09L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Monkey Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
LAG3/CD223/Lymphocyte activation gene 3 Protein
E21-J91	EnoGene	10ug	411.6 EUR
Rat Lymphocyte-Activation Gene 3 ELISA kit
E02L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Lymphocyte-Activation Gene 3 ELISA kit
E02L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Lymphocyte-Activation Gene 3 ELISA kit
E02L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Lymphocyte-Activation Gene 3 ELISA kit
E08L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Lymphocyte-Activation Gene 3 ELISA kit
E08L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Lymphocyte-Activation Gene 3 ELISA kit
E08L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Lymphocyte-Activation Gene 3 ELISA kit
E07L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Lymphocyte-Activation Gene 3 ELISA kit
E07L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Lymphocyte-Activation Gene 3 ELISA kit
E07L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Human), APC
4-PAB663Hu01-APC	Cloud-Clone	399.60 EUR 3735.60 EUR 1046.40 EUR 507.60 EUR 258.00 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with APC.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Human), Biotinylated
4-PAB663Hu01-Biotin	Cloud-Clone	363.60 EUR 2809.20 EUR 836.40 EUR 442.80 EUR 259.20 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with Biotin.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Human), Cy3
4-PAB663Hu01-Cy3	Cloud-Clone	483.60 EUR 4930.80 EUR 1345.20 EUR 627.60 EUR 294.00 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with Cy3.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Human), FITC
4-PAB663Hu01-FITC	Cloud-Clone	344.40 EUR 3012.00 EUR 860.40 EUR 430.80 EUR 230.40 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with FITC.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Human), HRP
4-PAB663Hu01-HRP	Cloud-Clone	366.00 EUR 3256.80 EUR 926.40 EUR 459.60 EUR 243.60 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with HRP.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Human), PE
4-PAB663Hu01-PE	Cloud-Clone	344.40 EUR 3012.00 EUR 860.40 EUR 430.80 EUR 230.40 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with PE.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Mouse), APC
4-PAB663Mu01-APC	Cloud-Clone	408.00 EUR 3843.60 EUR 1072.80 EUR 518.40 EUR 260.40 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with APC.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Mouse), Biotinylated
4-PAB663Mu01-Biotin	Cloud-Clone	368.40 EUR 2888.40 EUR 856.80 EUR 450.00 EUR 260.40 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with Biotin.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Mouse), Cy3
4-PAB663Mu01-Cy3	Cloud-Clone	493.20 EUR 5074.80 EUR 1381.20 EUR 642.00 EUR 297.60 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with Cy3.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Mouse), FITC
4-PAB663Mu01-FITC	Cloud-Clone	350.40 EUR 3098.40 EUR 882.00 EUR 439.20 EUR 232.80 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with FITC.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Mouse), HRP
4-PAB663Mu01-HRP	Cloud-Clone	373.20 EUR 3350.40 EUR 949.20 EUR 469.20 EUR 246.00 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with HRP.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Mouse), PE
4-PAB663Mu01-PE	Cloud-Clone	350.40 EUR 3098.40 EUR 882.00 EUR 439.20 EUR 232.80 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with PE.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Rat), APC
4-PAB663Ra01-APC	Cloud-Clone	421.20 EUR 4038.00 EUR 1122.00 EUR 538.80 EUR 266.40 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Rat Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with APC.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Rat), Biotinylated
4-PAB663Ra01-Biotin	Cloud-Clone	379.20 EUR 3031.20 EUR 892.80 EUR 464.40 EUR 265.20 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Rat Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with Biotin.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Rat), Cy3
4-PAB663Ra01-Cy3	Cloud-Clone	512.40 EUR 5334.00 EUR 1446.00 EUR 668.40 EUR 304.80 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Rat Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with Cy3.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Rat), FITC
4-PAB663Ra01-FITC	Cloud-Clone	361.20 EUR 3254.40 EUR 921.60 EUR 454.80 EUR 236.40 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Rat Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with FITC.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Rat), HRP
4-PAB663Ra01-HRP	Cloud-Clone	385.20 EUR 3519.60 EUR 992.40 EUR 486.00 EUR 250.80 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Rat Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with HRP.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Rat), PE
4-PAB663Ra01-PE	Cloud-Clone	361.20 EUR 3254.40 EUR 921.60 EUR 454.80 EUR 236.40 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Rat Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with PE.
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
20-abx152152	Abbexa	8534.40 EUR 4550.40 EUR 1054.80 EUR	10 × 96 tests 5 × 96 tests 96 tests
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
abx250327-96tests	Abbexa	96 tests	904.8 EUR
Mouse Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
abx514365-96tests	Abbexa	96 tests	801.6 EUR
Rat Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
abx514366-96tests	Abbexa	96 tests	801.6 EUR
Human Lymphocyte Activation Gene 3 (LAG3) CLIA Kit
20-abx492967	Abbexa	9567.60 EUR 5095.20 EUR 1177.20 EUR	10 × 96 tests 5 × 96 tests 96 tests
Mouse Lymphocyte Activation Gene 3 (LAG3) CLIA Kit
20-abx492968	Abbexa	10282.80 EUR 5472.00 EUR 1262.40 EUR	10 × 96 tests 5 × 96 tests 96 tests
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
abx571857-96tests	Abbexa	96 tests	904.8 EUR
Mouse Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
20-abx258497	Abbexa	8684.40 EUR 4626.00 EUR 1074.00 EUR	10 × 96 tests 5 × 96 tests 96 tests
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
DLR-LAG3-Hu-48T	DL Develop	48T	532.8 EUR
Description: A sandwich quantitative ELISA assay kit for detection of Human Lymphocyte Activation Gene 3 (LAG3) in samples from tissue homogenates, cell lysates or other biological fluids.
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
DLR-LAG3-Hu-96T	DL Develop	96T	687.6 EUR
Description: A sandwich quantitative ELISA assay kit for detection of Human Lymphocyte Activation Gene 3 (LAG3) in samples from tissue homogenates, cell lysates or other biological fluids.
Guinea pig Lymphocyte-Activation Gene 3 ELISA kit
E05L0344-192T	BlueGene	192 tests	1524 EUR
Description: A sandwich ELISA for quantitative measurement of Guinea pig Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Lymphocyte-Activation Gene 3 ELISA kit
E05L0344-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A sandwich ELISA for quantitative measurement of Guinea pig Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Lymphocyte-Activation Gene 3 ELISA kit
E05L0344-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A sandwich ELISA for quantitative measurement of Guinea pig Lymphocyte-Activation Gene 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
SEB663Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	5402.92 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Lymphocyte Activation Gene 3 (LAG3) in Tissue homogenates, cell lysates and other biological fluids.
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
SEB663Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	550.13 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Lymphocyte Activation Gene 3 (LAG3) in Tissue homogenates, cell lysates and other biological fluids.
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
SEB663Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	734.46 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Lymphocyte Activation Gene 3 (LAG3) in Tissue homogenates, cell lysates and other biological fluids.
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
SEB663Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	2945.08 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Lymphocyte Activation Gene 3 (LAG3) in Tissue homogenates, cell lysates and other biological fluids.
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
4-SEB663Hu	Cloud-Clone	5463.60 EUR 2886.00 EUR 735.60 EUR	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Lymphocyte Activation Gene 3 (LAG3) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.
Mouse Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
SEB663Mu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	5552.14 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Lymphocyte Activation Gene 3 (LAG3) in Tissue homogenates, cell lysates and other biological fluids.
Mouse Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
SEB663Mu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	562.42 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Lymphocyte Activation Gene 3 (LAG3) in Tissue homogenates, cell lysates and other biological fluids.
Mouse Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
SEB663Mu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	752.02 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Lymphocyte Activation Gene 3 (LAG3) in Tissue homogenates, cell lysates and other biological fluids.
Mouse Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
SEB663Mu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	3024.07 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Lymphocyte Activation Gene 3 (LAG3) in Tissue homogenates, cell lysates and other biological fluids.
Mouse Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
4-SEB663Mu	Cloud-Clone	5612.40 EUR 2965.20 EUR 752.40 EUR	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Lymphocyte Activation Gene 3 (LAG3) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.
Human Lymphocyte Activation Gene 3 ELISA Kit (LAG3)
RK01754	Abclonal	96 Tests	625.2 EUR
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
RDR-LAG3-Hu-48Tests	Reddot Biotech	48 Tests	549.6 EUR
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
RDR-LAG3-Hu-96Tests	Reddot Biotech	96 Tests	759.6 EUR
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
RD-LAG3-Hu-48Tests	Reddot Biotech	48 Tests	526.8 EUR
Human Lymphocyte Activation Gene 3 (LAG3) ELISA Kit
RD-LAG3-Hu-96Tests	Reddot Biotech	96 Tests	727.2 EUR
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Human), APC-Cy7
4-PAB663Hu01-APC-Cy7	Cloud-Clone	656.40 EUR 7327.20 EUR 1948.80 EUR 872.40 EUR 372.00 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with APC-Cy7.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Mouse), APC-Cy7
4-PAB663Mu01-APC-Cy7	Cloud-Clone	672.00 EUR 7543.20 EUR 2002.80 EUR 894.00 EUR 378.00 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with APC-Cy7.
Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody (Rat), APC-Cy7
4-PAB663Ra01-APC-Cy7	Cloud-Clone	699.60 EUR 7932.00 EUR 2100.00 EUR 933.60 EUR 388.80 EUR	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Rat Lymphocyte Activation Gene 3 (LAG3). This antibody is labeled with APC-Cy7.
Human Lymphocyte activation gene 3 protein(LAG3) ELISA kit
CSB-EL012719HU-24T	Cusabio	1 plate of 24 wells	198 EUR
Description: Quantitativesandwich ELISA kit for measuring Human Lymphocyte activation gene 3 protein (LAG3) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human Lymphocyte activation gene 3 protein(LAG3) ELISA kit
1-CSB-EL012719HU	Cusabio	843.60 EUR 5811.60 EUR 3084.00 EUR	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Lymphocyte activation gene 3 protein(LAG3) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Mouse Lymphocyte activation gene 3 protein(LAG3) ELISA kit
CSB-EL012719MO-24T	Cusabio	1 plate of 24 wells	198 EUR
Description: Quantitativesandwich ELISA kit for measuring Mouse Lymphocyte activation gene 3 protein (LAG3) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Mouse Lymphocyte activation gene 3 protein(LAG3) ELISA kit
1-CSB-EL012719MO	Cusabio	843.60 EUR 5811.60 EUR 3084.00 EUR	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Lymphocyte activation gene 3 protein(LAG3) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Human LAG3(Lymphocyte activation gene 3 protein) ELISA Kit
EH1083	FN Test	96T	628.92 EUR
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml
ELISA kit for Human Lymphocyte activation gene 3 protein
EK2439	SAB	96 tests	663.6 EUR
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Lymphocyte activation gene 3 protein in samples from serum, plasma, tissue homogenates and other biological fluids.
ELISA kit for Mouse Lymphocyte activation gene 3 protein
EK2440	SAB	96 tests	663.6 EUR
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Lymphocyte activation gene 3 protein in samples from serum, plasma, tissue homogenates and other biological fluids.
ELISA kit for Mouse LAG3 (Lymphocyte Activation Gene 3)
ELK5335	ELK Biotech	1 plate of 96 wells	518.4 EUR
Description: A sandwich ELISA kit for detection of Lymphocyte Activation Gene 3 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
ELISA kit for Human LAG3 (Lymphocyte Activation Gene 3)
ELK4745	ELK Biotech	1 plate of 96 wells	518.4 EUR
Description: A sandwich ELISA kit for detection of Lymphocyte Activation Gene 3 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Human LAG3/ Lymphocyte activation gene 3 protein ELISA Kit
E1415Hu	Sunlong	1 Kit	685.2 EUR
Mouse Lag3/ Lymphocyte activation gene 3 protein ELISA Kit
E0845Mo	Sunlong	1 Kit	685.2 EUR
Human Lymphocyte activation gene 3 protein, LAG3 ELISA KIT
ELI-03039h	Lifescience Market	96 Tests	988.8 EUR
Mouse Lymphocyte activation gene 3 protein, Lag3 ELISA KIT
ELI-03040m	Lifescience Market	96 Tests	1038 EUR
ELISA kit for Human LAG3 (Lymphocyte Activation Gene 3)
E-EL-H5466	Elabscience Biotech	1 plate of 96 wells	640.8 EUR
Description: A sandwich ELISA kit for quantitative measurement of Human LAG3 (Lymphocyte Activation Gene 3) in samples from Serum, Plasma, Cell supernatant
LAG3 (Lymphocyte-Activation Gene 3)/CD223 (Cluster of Differentiation 223)
MO47067	Neuromics	100 ul	418.8 EUR
Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)
CK56-10ug	Novoprotein	10ug	169.2 EUR
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)
CK56-1mg	Novoprotein	1mg	2008.8 EUR
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)
CK56-500ug	Novoprotein	500ug	1338 EUR
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)
CK56-50ug	Novoprotein	50ug	363.6 EUR
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Polyclonal Goat anti-GST p-form
GST-ANTI-3	Detroit R&D	50 uL	336 EUR
Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN	ImmunoStep	50 µg	418.8 EUR
T-lymphocyte activation antigen CD80 (CD80) Antibody
20-abx019054	Abbexa	410.40 EUR 109.20 EUR	100 ug 10 ug

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The analysis of the ROC curve has demonstrated the accuracy of the prediction of the prognostic models, because the area under the curve (AUC) was 0.742, 0.707 and 0.711 for LUAD, and 0.6668, 0.703 and 0.668 for LUSC, when the planned survival time were 1, 3 and 5 years, respectively. Mutation load analysis showed that the mutation level was associated with the risk score in LUAD patients. The analysis based on the geo and kaplan-meier tracer has demonstrated the prognostic validity of the models. As a result, LUAD and LUSC immune gene models can predict the prognosis. A complementary study of these genes can allow us to better distinguish between LUAD and LUSC and lead to an improvement in immunotherapy for lung cancer.