Cytogenetic and molecular genetic methods for chromosomal translocations detection with reference to the KMT2A/MLL gene

Cytogenetic and molecular genetic methods for chromosomal translocations detection with reference to the KMT2A/MLL gene

Acute leukemia (ALS) are often associated with chromosomal translocations, including KMT2A / MLL genes rearrangements. The identification or confirmation of these translocations is carried out by a number of genetic and molecular methods, some of which are regularly used in clinical practice, while others are mainly used for research purposes. In the clinic, these methods … Czytaj dalej